Ribociclib CAS No.:1256963-02-6

Ribociclib CAS No.:1256963-02-6

Ribociclib for advanced hormone receptor positive, HER2 negative breast cancer – first line

• ribociclib is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. Ribociclib specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Ribociclib does not currently have Marketing Authorisation in the EU for any indication. Ribociclib is in phase II studies for breast cancer

• Besides we also provide the Ribociclib intermediates

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