3-O-Ethyl-L-ascorbic Acid

Product Name

3-O-Ethyl-L-ascorbic acid

CAS number

86404-04-8

INCI

3-o-ethyl ascorbic acid

Features and efficacy

• Whitening

Physical and chemical properties and indicators

The content of the active substance

99.0%

appearance

White-to-class white crystalline powder

Assay content

≥99.0%

pH (3%, 20degrees C).

3.5~5.5

Water moisture

≤1.0%

Residue on ignition burns residue

＜0.5%

Solubility solubility

It is soluble in water

Product description

1. Chemical structure and name:

INCI Name: 3-o-ethyl ascorbic acid / 3-o-ETHYL ASCORBIC ACID

CASE No:86404-04-8

Molecular weight: 204.1

Molecular: C8H12O6

Chemical structure:

2. Product features:

VCE ascorbic acid ethyl ether is by far the best derivative of vitamin C, it is not only chemically stable, but also a derivative of the true meaning of the invariant vitamin C, and it enters the skin, and vitamin C metabolic pathways in the body, thus playing a better vitamin C effect.

Ascorbic acid ethyl ether is a hydrophilic oil-friendly sex material, 3 hydroxyl level introduced ethyl, not only enhance the stability of vitamin C, but also have hydrophilic and hydrophilic, making it easy to use in the formula, and this bisexual bi-parent structure material can easily pass through the layer and reach the dermis, high bioavailability, and pure vitamin C and other 2 bit derivatives are difficult to absorb and enter the skin.

2.1 Whitening

VCE is an active center copper ion (Cu2 plus) that suppresses the activity of tyrosinase Tyrosinase and effectively blocks the synthesis of melanin;

In vitro activity suppression experiments of tyrosine enzymes: a) tyrosine, doba;

In clinical tests, there was a significant improvement in skin color and skin clarity when adding 2% VCE

2.2 Wrinkle Anti-wrinkle

Vitamin C, as a skin antioxidant, removes oxygen free radicals from hydrophilic components and stimulates collagen synthesis; vitamin C is essential for the synthesis of collagen fibers and elastic fibers, and is an essential cofactory for proline hydroxylase and lysine hydroxylase, which catalyzes the synthesis of hydroxyproline and hydroxylytin to form the intersection of collagen molecules and collagen.

VCE ascorbic acid ethyl ether has repair collagen activity (including structure and synthesis) to promote the formation of skin cells and collagen synthesis based on the proportion of collagen consumed in skin cells, its activity level is similar to vitamin C sulfate.

2.3 Antioxidant Antioxidant Antioxidant

VCE is an effective antioxidant that is both hydrophilic and oil-friendly, reducing the occurrence of peroxides in fats in cosmetics and preventing product deterioration. VCE metabolizes in the body in the same way as normal vitamin C, and the ability to remove free radicals is comparable to that of normal vitamin C.

Table 1. A comparison of the effects of VCE's removal of organic free radical DPPH

2.5 Stability

VCE is a white, odorless crystal or crystalline powder made up of a stable ethyl vitamin C. VCE is where vitamin C is ethered at C3, and acetyl at C3 makes vitamin C inert and prevents VC from being destroyed by oxidation.

Analysis of the crystal structure of VCE: Melting point, MRI, infrared, MS, and elemental analysis of VCE have all proved that hydroxyl on bit 3 is replaced by an acetyl group and is a high purity substance.

2% VCE aqueous solution, examined by experimental conditions of 45degrees Cand 90 days of natural light, with no change in color and good stability.

2.6 Bioavaibility

Table 2. Comparison of VC content in vitamin C derivatives:

Packaging and storage

Package

1Kg/bag 5Kg/bag

expiration date

24 months

Storage conditions

Store in a cool (<25℃), dry, light-absorbing place, sealed and preserved

Experimental samples

IC50/μg

DPPH removal/g-g^-1

Lives. c

8.42

2.82

3-o-Ethyl

10.35

2.29

3-o-MAP

10.35

2.29

Name

molecular weight

Vitamin C content (%)

Vitamin C Vit. C

176.12

100

Vitamin C Ether VCE

204.18

86.3

Vitamin C glucoside AA2G

338.27

52.0

Vitamin C Phosphate Magnesium MAP

303.50

49.3

Vitamin C sodium phosphate SAP

358.08

46.5