Is There A Difference Between Octanoyl Hydroxamic Acid And Octanoyl Hydroxamic Acid?
Sep 15, 2019
Octanoyl hydroxamic acid is an ideal organic acid with excellent antibacterial and antibacterial properties at neutral pH and can be used in chemical preservative-free formulations. Octanoyl hydroxamic acid is an organic acid that remains in an ionized state from acidic to neutral and is the best antibacterial organic acid. It has high-efficiency chelation and inhibits the active elements required for mold, which limits the environment required for microbial growth. Octanoyl hydroxamic acid and most of the raw materials are compatible, and are not affected by the raw materials such as surfactants and proteins in the system, and can be compounded with preservatives such as alcohols and glycols. It can be added at normal temperature and high temperature. It is widely used in skin care and hair care products such as gels, essences, lotions, creams, shampoos and shower gels.
Characteristics of octanoic acid
Octanoyl hydroperic acid (CHA) has strong antifungal action, and its antibacterial principle is: CHA has high-efficiency selective chelation of Fe2+ and Fe3+. In the iron-limited environment, mold growth is limited. Iron is a key element in microbial growth, and microbial release of siderophores captures Fe3+ from the environment and converts it to Fe2+. CHA chelate Fe3+ has a high stability constant, which prevents mold from obtaining iron, and it is still effective when the pH is neutral, so it is an ideal organic acid for inhibition. CHA also has a short-chain activity, like octanediol, which also has the best carbon chain length to promote cell membrane structure degradation.
The CHA as an organic acid can inhibit the growth of mold only when it is dispersed in the product in an undissociated state, so CHA can only exert bacteriostatic efficacy in a neutral or acidic environment. CHA needs to use deionized water in the production, and add appropriate amount of chelating agent, such as EDTA-2Na, to avoid contact with copper ions and iron ions to overcome the possible discoloration phenomenon, which is of particular concern in use.
Octanoyl hydroxamic acid and octanoyl hydroxamic acid are synonymous with N-hydroxy-n-octylamide, and the same cas number is the same compound.
