Grasp The Peptide Of The Youth Key, And Open The High-speed Growth Anti-aging Cosmetics Golden Sub Track .

Peptides, as the third largest anti giant, have always been the star ingredients widely recognized by consumers in recent years, such as blue copper peptide, acetyl hexapeptide-1, snake venom like peptide, conotoxin peptide, etc., with high market demand and heat.

Peptides are a class of compounds formed by amino acids linked through peptide bonds, which are protein fragments with biological functions and are widely used in industries such as medicine, food health, and beauty and skincare. Moreover, due to the clear target of peptide action, clear mechanism, easy efficacy compounding, low immunogenicity and toxicity, and relatively cheap synthesis cost, peptide has been used in personal care products for nearly 50 years. Peptides can stimulate collagen synthesis, heal wounds, smooth wrinkles, whiten and anti-inflammatory, and are widely used in products such as whitening, antioxidant, and anti-aging.

At present, there is no strict unified definition and classification of peptides in different fields internationally. Generally speaking, peptides with 2-10 amino acids are called small molecule synthetic peptides, peptides with 11-100 amino acids are called oligopeptides, and peptides with more than 100 amino acids are called peptides.

The development and application of peptides have opened up a new field for cosmetics. More than 1200 peptide raw materials have been published internationally, while a total of 80 peptides are used in cosmetics sold in the market domestically. As an emerging market using peptides, it is expected that the market size will exceed 165 billion by 2024, indicating that there is still great potential and broad market prospects for the use of domestic peptides.

Peptide raw material category

According to the frequency of use and composition in cosmetics, they can be divided into general oligopeptides, acetyl oligopeptides, palmitoyl oligopeptides, etc. After conducting research on peptide raw materials used in wrinkle resistant cosmetics, peptide raw materials can also be divided into three categories based on the analysis of their mechanism of action: signaling, neurotransmitter inhibition, and carrier. Different peptides have different effects. Next, a more detailed analysis will be conducted on the different mechanisms of action.

01. signal peptide

"Signal peptide" is the most commonly used peptide, which can send or simulate signals in the process of extracellular matrix protein synthesis. Mainly through the promotion of extracellular matrix synthetase and inhibition of metalloproteinase, it can regulate the protein turnover of skin tissue, increase the synthesis of extracellular matrix such as collagen, Elastin and proteoglycan, make skin tight and delay aging.

The main signal peptide include palmitoyl tripeptide-1, palmitoyl pentapeptide-4, palmitoyl tripeptide-5, palmitoyl oligopeptide palmitoyl tetrapeptide-7, palmitoyl hexapeptide-12, tripeptide-1, palmitoyl tripeptide-38, acetyl tetrapeptide-5, etc.

02. Neurotransmitter inhibitory peptides

Human aging often starts with the appearance of fine lines on the face, such as the corners of the eyes, mouth, forehead, and other areas. Neurotransmitter inhibitory peptides inhibit acetylcholine transmission, which can locally block nerve transmission of muscle contraction information, allowing facial muscles to relax and achieve the effect of smoothing fine lines. It can have a nerve blocking effect similar to botulinum toxin, but it does not bring the side effects of botulinum toxin, so it is widely used in anti wrinkle products.

The main neurotransmitter inhibitory peptides include acetyl hexapeptide-8, acetyl hexapeptide-1, dipeptide diaminobutyryl benzylamide di acetate (snake venom like peptide), acetyl dipeptide-1 cetyl ester, etc.

03. Carrier Peptide

Carrier peptides refer to peptides that can accelerate and promote the entry of bioactive molecules into the skin, also known as cell penetrating peptides or membrane transduction peptides, and can promote the transportation process of various proteins into cells. The application of carrier peptides in cosmetics is mainly used to resist skin photoaging. The main carrier peptides include copper tripeptide-1 and manganese tripeptide-1, which reduce wrinkles and pigment precipitation related to photoaging, respectively.

Due to the diversity of peptide structures, there is a diversity of biological activities. In addition to the aforementioned peptide components, there are also antioxidant, antibacterial and other active peptides, as well as sub categories such as enzyme inhibitory peptides and antibacterial peptides. Enzyme inhibitory peptides can directly or indirectly inhibit the formation of some enzymes or alter their activity. Antibacterial peptides have the ability to kill and inhibit the growth of various microorganisms, playing an important role in the construction of skin microbiota and the maintenance of skin barrier functions.

In addition, there is also collagen peptide, which can cut large molecule collagen into small molecule peptides that can be directly absorbed by the human body, with a higher absorption rate. The oral beauty market naturally targets peptides, with clear intentions to dig gold.

Application of Peptide Raw Materials

The beauty industry is a very special and lively industry, with constantly segmented categories and emerging brands joining the battlefield. The trend of ingredient composition in trendy raw materials has never been so clear. Hot raw materials not only need to be used, but also need to be different, using extreme, higher concentration additives, more scientific formulas, more specialized ingredients, etc. Peptides have been added from the original single ingredient to the current multiple peptide ratio, and the synergistic effect of ingredient peptides has been specially studied to create a more comprehensive anti-aging and anti-aging system.

The anti-aging products launched by major brands on the market now use not only one peptide, but also multiple peptide synergy. It not only promotes the generation of collagen, but also inhibits the transmission of acetylcholine, smoothes fine lines, and provides anti-aging materials for the lower foot to maximize the anti-aging effect of the product. Main signal peptide series

In the era of effective skincare, high-quality skincare does not depend on the amount of products used, but on the effective ingredients that can be absorbed by the skin. Therefore, powerful peptide raw materials will be an indispensable ingredient in this market in the future.

Anti aging skincare products are one of the most promising consumer markets, with the global market size of anti aging products reaching $216 billion in 2021, a year-on-year increase of 7.5%.

The application of peptides in cosmetics has shown an increasing trend year by year, and there has also been a significant increase in the number of related patent research and publication publications. These trends all predict that peptide raw materials will become an evergreen ingredient in the future, and with deeper research and development, they will create a larger market.

Especially the edible collagen peptide, in the trend of homologous makeup and food, is also a major benefit for the oral beauty market. In addition to synthetic peptides, there are also natural peptides derived from animals, plants, microorganisms, etc. that have been hydrolyzed or extracted. And currently, there are only 80 types of peptide raw materials available in China, while more than 1200 types of peptide raw materials can be applied internationally. It is foreseeable that in the future, research and application of new active peptides will become increasingly widespread. The exploration and development of peptides cannot be ignored, and may become a key factor in the growth of several industries in the future.